Welcome to Translational Phototherapeutics Laboratory
Led by A/Prof Daniel Teh Boon Loong
Advancing light-based therapies from bench to bedside for effective treatment of medical conditions.
Introduction
Our lab, led by focuses on phototherapeutics such as optogenetics and photodynamic therapy (PDT) to address vision loss and neurological disorders affecting the visual system.
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Optogenetics for Vision Restoration: Use of optogenetic tools to restore vision in retinal dystrophies by engineering light-sensitive proteins into degenerated photoreceptors.
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PDT in Disease Modeling: We utilize photodynamic therapy (PDT) to induce pathological changes in ocular tissues. These models enable us to study disease progression and test novel therapeutic interventions.
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Wireless PDT Implants: We are pioneering near-infrared wireless implants for comfortable and precise PDT delivery, enhancing treatment efficacy and patient comfort.
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Our research aims to advance vision therapeutics and neurological treatments, improving outcomes for patients with visual impairments.
Glaviano, A., Foo, A. S. C., Lam, H. Y., Yap, K. C. H., Jacot, W., Jones, R. H., Eng, H., Nair, M. G., Makvandi, P., Geoerger, B., Kulke, M. H., Baird, R. D., Prabhu, J. S., Carbone, D., Pecoraro, C., Teh, D. B. L., Sethi, G., Cavalieri, V., Lin, K. H., Javidi-Sharifi, N. R., … Kumar, A. P. (2023). PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer. Molecular cancer, 22(1), 138. https://doi.org/10.1186/s12943-023-01827-6
Kamarudin, J. B. M., Sun, B., Foo, A. S. C., Lim, X. Y., Judd, H., Tan, X., Tan, X. H., Razar, R. B. B. A., Liu, M., Zhong, J., Chua, J. J. E., Ng, C. W. Q., Goh, J. C. H., Tan, T. Z., Parikh, B. H., Su, X., Kumar, A. P., Ong, W. Y., Yamaguchi, N., Set, S. Y., … Teh, D. B. L. (2023). SIRIUS, Ultra-Scintillating Upconversion Breast Implant for Remote Orthotopic Photodynamic Therapy. ACS nano, 17(12), 11593–11606. https://doi.org/10.1021/acsnano.3c01916
Publication
Teh, D. B. L., Lim, K. L., Chai, C., Kennedy, B. K., Yong, Z., & Bansal, A. (2023, February 9). US20230045729A1 - implantable light delivery device. Google Patents. https://patents.google.com/patent/US20230045729A1/en